Rheological properties of hyaluronic acid-based fillers for facial cosmetic aesthetics

Hyaluronic acid-based dermal fillers are the most used materials in cosmiatry, and their clinical implications linked to viscoelastic properties. This study aimed determine rheological behavior of HA products Brazil by changing specific physicochemical characteristics under different test frequencies. Laboratory analyses 0.9 mL samples were performed a TA-Instruments AR-1500ex Rheometer at 25 °C, oscillation frequencies 100, 10, 1, 0.1 radians/second, considering measurements G′, G′′, Tan δ. The value G' increased as increased. In parallel, changes G" ones that varied for 1 radian/second. maximum was observed with Hialurox Ultra Lift® 26 mg/g (793.45; 554.06; 423.44 Pa, 10 rad/s, respectively). While lowest values obtained Rennova Deep® (43.01; 19.75; 10.75 10.42 Pa rad/sec, occurred investigated properties indicated hyaluronic vary when subjected conditions shear rate, which should be considered indication choosing appropriate material according region treated.